一、个人简介：

杨璐，河南大学基础医学院，教师。

二、主要研究方向：

肿瘤发病机理研究。

三、承担的研究项目：

作为项目负责人承担中国博士后科学基金1项。

四、已发表论文：

[9] Sheng Li§, *, Bo-Wen Zhang§, Qian-Qian Lou, Yue Liu, Zi-Juan Wei, Jing Huang, Kun-Hou Yao, Qian-Ru Xu, Juan Fan, Yan Xi, Lu Yang*, Su Chen*. (2024) ATG5 nonautophagically regulates inflammation and differentiation in mouse embryonic stem cells. Autophagy 20(8): 1897-1898. (Invited Paper，共同通讯作者)

[8] Bo-Wen Zhang, Zi-Juan Wei, Qian-Qian Lou, Yue Liu, Jing Huang, Kun-Hou Yao, Yan Xi, Su Chen, Lu Yang*, Sheng Li*. (2024) Protocol to test for the formation of ternary protein complexes in vivo or in vitro using a two-step immunoprecipitation approach. STAR Protocols 5(2):103080. (Invited Paper，共同通讯作者)

[7] Sheng Li§, Jin Sun§, Bo-Wen Zhang§, Lu Yang§, Ying-Cui Wan, Bei-Bei Chen, Nan Xu, Qian-Ru Xu, Juan Fan, Jia-Ni Shang, Rui Li, Chen-Ge Yu, Yan Xi*, Su Chen*. (2024) ATG5 attenuates inflammatory signaling in embryonic stem cells to control differentiation. Developmental Cell 59(7): 882-897. (共同第一作者)

[6] Lu Yang, Bo Wang, Xinyan Jiao, Can Zhou, Su Chen, Xiaoqian Gao, Wei Sun, Shaoran Song, Juan Li, Jie Liu, Yaochun Wang, Peijun Liu*. (2021) TAZ maintains telomere length in TNBC cells by mediating Rad51C expression. Breast Cancer Research 23(1): 89. (第一作者)

[5] Lu Yang, Xing Wang, Xinyan Jiao, Bixia Tian, Miao Zhang, Can Zhou, Ruiqi Wang, He Chen, Bo Wang, Juan Li, Jie Liu, Guanjun Zhang*, Peijun Liu*. (2020) Suppressor of Ty 16 promotes lung cancer malignancy and is negatively regulated by miR-1227-5p. Cancer Science 111(11): 4075-4087. (第一作者)

[4] Yanping Liu§, Yufei Wang§, Lu Yang§, Feng Sun§, Sheng Li§, Yequan Wang, Guo-An Zhang, Tingting Dong, Lei-Lei Zhang, Wanglin Duan, Xiaojun Zhang*, Wen Cui*, Su Chen*. (2021) The nucleolus functions as the compartment for histone H2B protein degradation. iScience 24(4): 102256. (共同第一作者)

[3] Yufei Wang§, Lu Yang§, Xiaojun Zhang§, Wen Cui*, Yanping Liu, Qin-Ru Sun, Qing He, Shiyan Zhao, Guo-An Zhang, Yequan Wang, Su Chen*. (2019) Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53. EMBO Reports 20(7): e47563. (共同第一作者)

[2] Xin Huang§, Lu Yang§, Feng-Feng Cai§, Yufei Wang, Ping Chen, Jiangsheng Mi, Chenghua Yu, Jianghua Lai, Xiaojun Zhang, Shuguang Wei, Wen Cui*, Su Chen*. (2017) Autophagy-related protein ATG5 regulates Histone H2B mono-ubiquitylation by translational control of RNF20. Journal of Genetics and Genomics 44(10): 503-506. (共同第一作者)

[1] Hongli An§, Lu Yang§, Chen Wang§, Zhixue Gan§, Haihui Gu§, Tao Zhang, Xin Huang, Yan Liu, Yufeng Li, Shing-Jyh Chang, Jianghua Lai, Ya-Bin Li, Su Chen*, Fang-Lin Sun*. (2017) Interactome analysis reveals a novel role for RAD6 in the regulation of proteasome activity and localization in response to DNA damage. Molecular and Cellular Biology 37(6): e00419-16. (共同第一作者)

五、讲授课程：

本科生学位课程：《医学细胞生物学》、《医学遗传学》

六、联系方式（邮箱等）：

lu_yang0224@163.com