一、个人简介：

郑善清，博士，教授，河南大学高层次人才黄河学者。

2010-2013，中国科学院大学，博士

2014-2019，女王大学(Queen’s University, Canada)，博士后

2019至今，河南大学基础医学院，教授

二、主要研究方向：

目前主要研究营养与衰老及衰老相关疾病的关系，其中包括营养因子、维生素和氨基酸单体等对衰老的影响；核糖体、蛋白质稳态与长寿的关系；以及间歇性节食对衰老和健康的影响。

三、已发表论文：

15. Xue Yin, Fangzhou Dai, Dongyang Ran, Yutong Zhang, Zhi Qu, Shanqing Zheng. Cysteine protease cathepsin B promotes lysosome integrity to extend the lifespan of alternative day fasting worms. Aging Cell. 2024;00:e14286. DOI: 10.1111/acel.14286 (2024). 通讯作者，一区TOP，IF 8.0

14. Wei Zhao, Ruiting Huang, Dongyang Ran, Yutong Zhang, Zhi Qu, Shanqing Zheng. Inhibiting HSD17B8 suppresses the cell proliferation caused by PTEN failure. Scientific Reports, (2024) 14:12280, doi:10.1038/s41598-024-63052-5. 通讯作者，二区，IF 4.60

13. Zhi Qu, Limin Liu, Xiaoliang Wu, Peisen Guo, Zengli Yu, Peixi Wang, Yuzhen Song, Shanqing Zheng & Nan Liu. Cadmium-induced reproductive toxicity combined with a correlation to the oogenesis process and competing endogenous RNA networks based on a Caenorhabditis elegans model. Ecotoxicology and Environmental Safety 268, doi:10.1016/j.ecoenv.2023.115687 (2023). 通讯作者，二区TOP，IF 6.800

12. Zhi Qu, Lu Zhang, Wei Huang & Shanqing Zheng. Vitamin K2 Enhances Fat Degradation to Improve the Survival of C. elegans. Frontiers in Nutrition 9, doi:10.3389/fnut.2022.858481 (2022). 通讯作者，一区TOP，IF 6.590

11. Zhi Qu, Chunqian Feng, Virginia K. Walker, Wenyi Kang, Nan Liu & Shanqing Zheng. Effects of sugar addition on adipolysis and volatile profiles of dry cured sausage. Journal of Future Foods 2, 184-191, doi:10.1016/j.jfutfo.2022.03.001 (2022). 通讯作者，IF 5.20

10. Zhi Qu, Chunqian Feng, Ruiling Li, Nan Liu & Shanqing Zheng. Characteristic and effect analysis of protein and peptide in Cantonese cured meat processing. Food Science and Human Wellness 11, 1392-1401, doi:10.1016/j.fshw.2022.04.028 (2022).通讯作者，一区TOP，IF 8.022

9. Zhi Qu, Shaoping Ji & Shanqing Zheng. Glucose and cholesterol induce abnormal cell divisions via DAF-12 and MPK-1 in C. elegans. Aging-Us 12, 16255-16269 (2020). 通讯作者，二区TOP，IF 5.682

8. Zhi Qu, Shaoping Ji & Shanqing Zheng. BRAF Controls the Effects of Metformin on Neuroblast Cell Divisions in C. elegans. International journal of molecular sciences 22, doi:10.3390/ijms22010178 (2020). 通讯作者，二区TOP，IF 5.923

7. Shanqing Zheng, Zhi Qu, Michael Zanetti, Brandon Lam & Ian Chin-Sang. C. elegans PTEN and AMPK block neuroblast divisions by inhibiting a BMP-insulin-PP2A-MAPK pathway. Development 145, doi:10.1242/dev.166876 (2018). 第一作者，二区TOP，IF 6.868

6. Shanqing Zheng, Hilton Chiu, Jeffrey Boudreau, Tony Papanicolaou, William Bendena & Ian Chin-Sang. A functional study of all 40 Caenorhabditis elegans insulin-like peptides. The Journal of biological chemistry 293, 16912-16922, doi:10.1074/jbc.RA118.004542 (2018). 第一作者，二区TOP，IF 5.157

5. Shanqing Zheng, Xiaobing Huang, Tikun Xing, Aijun Ding, Guisheng Wu & Huairong Luo. Chlorogenic Acid Extends the Lifespan of Caenorhabditis elegans via Insulin/IGF-1 Signaling Pathway. The journals of gerontology. Series A, Biological sciences and medical sciences 72, 464-472, doi:10.1093/gerona/glw105 (2017). 第一作者，一区TOP，IF 6.053

4. Shanqing Zheng & Ian D. Chin-Sang. C. elegans Methods to Study PTEN. Methods in Molecular Biology, 307-321, doi:10.1007/978-1-4939-3299-3_17 (2016).

3. Shanqing Zheng, Sentai Liao, Yuxiao Zou, Zhi Qu, Weizhi Shen & Ying Shi. Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegans. Age (Dordr) 36, 9719, doi:10.1007/s11357-014-9719-z (2014). 通讯、第一作者，二区，IF 3.390

2. Shanqing Zheng, Sentai Liao, Yuxiao Zou, Zhi Qu & Fan Liu. ins-7 Gene expression is partially regulated by the DAF-16/IIS signaling pathway in Caenorhabditis elegans under celecoxib intervention. PloS one 9, e100320, doi:10.1371/journal.pone.0100320 (2014). 通讯、第一作者，三区，IF 3.23

1. Shanqing Zheng, Aijun Ding, Guoping Li, Guisheng Wu & Huairong Luo. Drug absorption efficiency in Caenorhbditis elegans delivered by different methods. PloS one 8, e56877, doi:10.1371/journal.pone.0056877 (2013).第一作者，三区，IF 3.53

四、联系方式（邮箱等）：zhengshanqing@henu.edu.cn